The Meraki management profile must be present on all devices enrolled in a Systems Manager network. To maintain communication between the Meraki Dashboard and the device, there are several policies that can be implemented to prevent or discourage end users from deleting this profile.
iOS and OS X profiles can be made mandatory and unremovable if installed through Apple's DEP program. See the DEP article for instructions on how to push supervised settings and restrict removal.
OS X devices can also be configured in Systems manager > MDM > Settings to prompt for a password when users try to remove the management profile.
Deploy a preferred, password-protected or encrypted wireless profile to devices using Systems Manager. This will allow for the credentials to be only known by Systems Manager administrators. As a result, any device will need to retain the previously provisioned wireless profile to have network access.
iOS and Android apps that are pushed out using Systems Manager can be set to uninstall upon removal of the Meraki management profile using the Remove With MDM flag. Removing apps will leave devices with a limited set of basic features.
Configure an email alert under Systems manager > Configure > Alerts to notify your dashboard admins when a profile is removed. You can also monitor at a high level which devices have had their profiles removed by adding the column "Managed?" in Systems manager > Monitor > Clients.